Anti-Phospho-FADD (S194) Antibody

• Description:

  Boster Bio Anti-Phospho-FADD (S194) Antibody catalog # A00237S194. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADD; FADD; MORT1; GIG3;

• Gene Name:

  FADD

• UniProt:

  Q13158

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human FADD around the phosphorylation site of Ser194. AA range:159-208

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.

• Applications:

  WB, IHC, ELISA

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

• Molecular Weight:

  23279 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  FAS-associated death domain protein

• Protein Name:

  FAS-associated death domain protein