Anti-Phospho-Ataxin-1 (S776) ATXN1 Antibody

• Description:

  Boster Bio Anti-Phospho-Ataxin-1 (S776) ATXN1 Antibody catalog # A01786S776. Tested in ELISA, IF, IHC-P, WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  Ataxin-1; Spinocerebellar ataxia type 1 protein; ATXN1; ATX1, SCA1;

• Gene Name:

  ATXN1

• UniProt:

  P54253

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human Ataxin 1 around the phosphorylation site of Ser776. AA range:742-791

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed throughout the body.

• Applications:

  ELISA, IF, IHC-P, WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249) . In concert with CIC and ATXN1L, involved in brain development (By similarity) .

• Molecular Weight:

  86923 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Ataxin-1

• Subcellular Location:

  Cytoplasm

• Protein Name:

  Ataxin-1