Anti-Phospho-CD28 (Y218) Antibody

• Description:

  Boster Bio Anti-Phospho-CD28 (Y218) Antibody catalog # A00065Y218. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  T-cell-specific surface glycoprotein CD28; TP44; CD28; CD28;

• Gene Name:

  CD28

• UniProt:

  P10747

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CD28 around the phosphorylation site of Tyr218. AA range:171-220

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in T-cells and plasma cells, but not in less mature B-cells.

• Applications:

  WB, ELISA

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933) . Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037) .

• Molecular Weight:

  25066 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  T-cell-specific surface glycoprotein CD28

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.

• Protein Name:

  T-cell-specific surface glycoprotein CD28