Anti-Interleukin-23 receptor IL23R Antibody

• Description:

  Boster Bio Anti-Interleukin-23 receptor IL23R Antibody catalog # A00607-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  Interleukin-23 receptor; IL-23 receptor; IL-23R; IL23R;

• Gene Name:

  IL23R

• UniProt:

  Q5VWK5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells.

• Applications:

  WB, ELISA

• Purification:

  IL23R antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Form:

  Liquid

• Function:

  Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

• Molecular Weight:

  71722 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Interleukin-23 receptor

• Subcellular Location:

  Cell membrane

• Protein Name:

  Interleukin-23 receptor