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Anti-FLRT3 Antibody

CAT: 0519-A06175Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06175Size:100 µL
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Description
Boster Bio Anti-FLRT3 Antibody catalog # A06175. Tested in ELISA, WB applications. This antibody reacts with Human, Rat.
Synonyms
Leucine-rich repeat transmembrane protein FLRT3; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; FLRT3; KIAA1469; UNQ856/PRO1865;
Gene Name
FLRT3
UniProt
Q9NZU0
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Tissue Specificity
Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.
Applications
WB, ELISA
Purification
FLRT3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity) . Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030) . Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity) . Promotes neurite outgrowth (in vitro) (PubMed:14706654) . Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity) .
Molecular Weight
73004 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Leucine-rich repeat transmembrane protein FLRT3
Subcellular Location
Cell membrane
Protein Name
Leucine-rich repeat transmembrane protein FLRT3