Anti-FLRT3 Antibody

• Description :

  Boster Bio Anti-FLRT3 Antibody catalog # A06175. Tested in ELISA, WB applications. This antibody reacts with Human, Rat.

• Synonyms :

  Leucine-rich repeat transmembrane protein FLRT3; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; FLRT3; KIAA1469; UNQ856/PRO1865;

• Gene Name :

  FLRT3

• UniProt :

  Q9NZU0

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Tissue Specificity :

  Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.

• Applications :

  WB, ELISA

• Purification :

  FLRT3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Form :

  Liquid

• Function :

  Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity) . Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030) . Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity) . Promotes neurite outgrowth (in vitro) (PubMed:14706654) . Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity) .

• Molecular Weight :

  73004 MW

• Shipping Conditions :

  Available

• Storage Conditions :

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment :

  IgG

• Other Gene Names :

  Leucine-rich repeat transmembrane protein FLRT3

• Subcellular Location :

  Cell membrane

• Protein Name :

  Leucine-rich repeat transmembrane protein FLRT3