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Anti-TRRAP Antibody

CAT: 0519-A02981Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A02981Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-TRRAP Antibody catalog # A02981. Tested in IHC applications. This antibody reacts with Human, Mouse.
Synonyms
Transformation/transcription domain-associated protein;350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homolog; TRRAP; PAF400;
Gene Name
TRRAP
UniProt
Q9Y4A5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
IHC
Purification
TRRAP antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Form
Liquid
Function
Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1- like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Molecular Weight
437600 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Transformation/transcription domain-associated protein
Subcellular Location
Nucleus
Protein Name
Transformation/transcription domain-associated protein

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