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Anti-SLAP1 Antibody

CAT: 0519-A00418Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A00418Size:100 µL
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Description
Boster Bio Anti-SLAP1 Antibody catalog # A00418. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Src-like-adapter; Src-like-adapter protein 1; SLAP-1; hSLAP; SLA; SLAP, SLAP1;
Gene Name
SLA
UniProt
Q13239
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Tissue Specificity
Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.
Applications
WB, ELISA
Purification
SLAP1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Molecular Weight
31156 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Src-like-adapter
Subcellular Location
Cytoplasm . Endosome . Colocalizes with endosomes. .
Protein Name
Src-like-adapter

UniProtKB · Q13239

Src-like-adapter

SLAP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13239
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7Z4J2, B7Z4L6, Q6FI01, Q9UMQ8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndosome

PTM

LipoproteinMyristatePhosphoprotein

Domain

SH2 domainSH3 domain

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