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Glycyrin

CAT: 0804-HY-N3960-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3960-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity[1][2][3].
CAS Number
66056-18-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; PPAR
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glycyrin.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(O)C=C2O)=CC3=C(OC)C(C/C=C(C)\C)=C(OC)C=C3O1
Molecular Formula
C22H22O6
Molecular Weight
382.41
Precautions
H302, H315, H319, H335
References & Citations
[2]Tanaka Y, et, al. Antibacterial compounds of licorice against upper airway respiratory tract pathogens. J Nutr Sci Vitaminol (Tokyo) . 2001 Jun;47 (3) :270-3.|[3]Wang Q, et, al. Metabolites identification of glycyrin and glycyrol, bioactive coumarins from licorice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 1:983-984:39-46.|[1]Kuroda M, et, al. Phenolics with PPAR-gamma ligand-binding activity obtained from licorice (Glycyrrhiza uralensis roots) and ameliorative effects of glycyrin on genetically diabetic KK-A (y) mice. Bioorg Med Chem Lett. 2003 Dec 15;13 (24) :4267-72.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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