Products for Research Use Only
RegisterLogin

Anti-S1PR2 Antibody

CAT: 0519-A02904Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-A02904Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The Sphingosine 1-phosphate receptor 2 (S1PR2) protein was initially identified as G-protein coupled receptor thought to be involved in development (1) and was found to mediate sphingosine 1-phosphate (SPP) -induced cell rounding and neurite retraction (2) . S1PR2 and the related protein S1PR3 (also known as EDG3) are also thought to mediate the SPP-induced cell proliferation, survival, and related signaling events (3) . S1PR2 has also been found to be key regulator in acute vascular inflammation and may be a novel therapeutic target for vascular disorders (4) .
Description
Boster Bio Anti-S1PR2 Antibody (Catalog # A02904) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Sphingosine 1-phosphate receptor 2, S1P2, AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2
Gene Name
S1PR2
UniProt
O95136
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
S1PR2 antibody is human, mouse and rat reactive.
Immunogen
S1PR2 antibody was raised against an 16 amino acid peptide near the carboxy terminus of human S1PR2. The immunogen is located within amino acids 270 - 320 of S1PR2.
Clonality
Polyclonal
Applications
ELISA, WB, IHC-P, IF
Field of Research
Stem Cells, Signal Transduction, Immunology
Purification
S1PR2 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P) (PubMed:10617617) . S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (PubMed:10617617) . When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis (PubMed:10617617) . Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251) . Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity) .
Molecular Weight
38867 MW
Shipping Conditions
Available
Storage Conditions
S1PR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Fragment
IgG
Other Gene Names
Sphingosine-1-phosphate receptor 2
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Name
Sphingosine-1-phosphate receptor 2

UniProtKB · O95136

Sphingosine 1-phosphate receptor 2

S1PR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95136
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
S1PR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
S1P receptor 2, S1P2
EC number
—
Processing
—
Secondary accessions
Q86UN8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

Disease

DeafnessDisease variantNon-syndromic deafness

Molecular function

G protein-coupled receptorReceptorTransducer

PTM

GlycoproteinLipoproteinPalmitate

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
LS009294S1PR2 (NM_004230) Human Over-expression Lysate
LS009294-20ugS1PR2 (NM_004230) Human Over-expression Lysate
LS009294-100ugS1PR2 (NM_004230) Human Over-expression Lysate
A01502-3Anti-EDG1/S1PR1 Antibody
A01502-2Anti-EDG1 S1PR1 Antibody
A01502Anti-S1P1 S1PR1 Antibody
A01502-1Anti-EDG-1 S1PR1 Antibody
A09413-1Anti-EDG-6 S1PR4 Antibody
A03755-1Anti-EDG-3 S1PR3 Antibody
M03755Anti-S1PR3 Rabbit Monoclonal Antibody

Alternative Products

CatalogName
MBS8325568-01Anti-s1pr2 Antibody
MBS422443-01Goat anti-S1PR2 Antibody
GTR18118831-01S1PR2 Antibody

Popular Products