Anti-Adenosine receptor A2b ADORA2B Antibody

• Background:

  The adenosine receptor ADORA2B is a member of the G protein-coupled receptor superfamily and is an integral membrane protein that stimulates adenylate cyclase activity in the presence of adenosine (1,2) . Extracellular adenosine triggers a potent anti-inflammatory response that is mediated in part by ADORA2B including the stimulation of IL-10 production (3-5) . Activation of ADORA2B can also enhance the abundance of regulatory T cells (Tregs), a class of cells that work to constrain inflammation (6) .

• Description:

  Boster Bio Anti-Adenosine receptor A2b ADORA2B Antibody (Catalog # A05238) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Adenosine receptor A2b, ADORA2

• Gene Name:

  ADORA2B

• UniProt:

  P29275

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Cross Reactivity:

  ADORA2B antibody is human, mouse and rat reactive. At least two isoforms of ADORA2B are known to exist; this antibody will detect both isoforms. ADORA2B antibody is predicted to not cross-react with ADORA2A.

• Immunogen:

  ADORA2B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ADORA2B. The immunogen is located within the last 50 amino acids of ADORA2B.

• Clonality:

  Polyclonal

• Applications:

  ELISA, WB, IHC-P, IF

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  ADORA2B antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Form:

  Liquid

• Function:

  Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

• Molecular Weight:

  36333 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  ADORA2B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

• Fragment:

  IgG

• Other Gene Names:

  Adenosine A2b receptor

• Subcellular Location:

  Cell membrane; Multi-pass membrane protein.

• Prediction Reactivity:

  Rabbit

• Protein Name:

  Adenosine A2b receptor