Anti-Synaptogyrin-1 SYNGR1 Antibody

• Background:

  Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

• Description:

  Boster Bio Anti-Synaptogyrin-1 SYNGR1 Antibody (Catalog # A10148) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Synaptogyrin-1

• Gene Name:

  SYNGR1

• UniProt:

  O43759

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  SYNGR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human SYNGR1. The immunogen is located within amino acids 120 - 170 of SYNGR1.

• Clonality:

  Polyclonal

• Applications:

  ELISA, WB, IHC-P, IF

• Field of Research:

  Neuroscience

• Purification:

  SYNGR1 Antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Form:

  Liquid

• Function:

  May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity) . Involved in the regulation of short-term and long-term synaptic plasticity (By similarity) .

• Molecular Weight:

  25456 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Other Gene Names:

  Synaptogyrin 1

• Subcellular Location:

  Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane

• Protein Name:

  Synaptogyrin 1