Anti-FABP7 Antibody

• Background:

  FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.

• Description:

  Boster Bio Anti-FABP7 Antibody (Catalog # A02646) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.

• Synonyms:

  MRG, BLBP, FABPB, B-FABP, MRG, Fatty acid-binding protein, brain, Brain lipid-binding protein

• Gene Name:

  FABP7

• UniProt:

  O15540

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7. The immunogen is located within the last 50 amino acids of FABP7.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in brain and other neural tissues.

• Applications:

  ELISA, WB, IHC-P

• Field of Research:

  Homeostasis

• Purification:

  FABP7 Antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Form:

  Liquid

• Function:

  B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity) . .

• Molecular Weight:

  14889 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  FABP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Other Gene Names:

  Fatty acid binding protein 7, brain

• Subcellular Location:

  Cytoplasm.

• Prediction Reactivity:

  Bovine, Chicken, Rat, Mouse

• Protein Name:

  Fatty acid binding protein 7, brain