Anti-Spermidine synthase/SRM Antibody Picoband®

Anti-Spermidine synthase/SRM Antibody Picoband®

• Background: The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
• Description: Boster Bio Anti-Spermidine synthase/SRM Antibody Picoband® catalog # A01594-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
• Synonyms: Neutrophil cytosol factor 1; NCF-1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox; NCF1; NOXO2; SH3PXD1A
• CAS Number: 9007-83-4
• Gene Name: neutrophil cytosolic factor 1
• Gene ID: 6723
• UniProt: P19623
• Host: Rabbit
• Reactivity: Human
• Cross Reactivity: No cross-reactivity with other proteins.
• Immunogen: E.coli-derived human Spermidine synthase/SRM recombinant protein (Position: A15-E292).
• Clonality: Polyclonal
• Applications: WB,Flow Cytometry,ELISA
• Purification: Immunogen affinity purified.
• Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Form: Lyophilized
• Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Function: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
• References & Citations: 1. Myohanen, S., Kauppinen, L., Wahlfors, J., Alhonen, L., Janne, J. Human spermidine synthase gene: structure and chromosomal localization. DNA Cell Biol. 10: 467-474, 1991. 2. Wahlfors, J., Alhonen, L., Kauppinen, L., Hyvonen, T., Janne, J., Eloranta, T. O. Human spermidine synthase: cloning and primary structure. DNA Cell Biol. 9: 103-110, 1990. Note: Erratum: DNA Cell Biol. 9: 543 only, 1990. 3. Winqvist, R., Alanen, L., Grzeschik, K.-H., Janne, J., Eloranta, T. Mapping of DNA sequences for spermidine synthase to human chromosome 1p36-p22 and chromosome 3p14-q21. (Abstract) Cytogenet. Cell Genet. 58: 1865 only, 1991.
• Storage Conditions: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
• Calculated Molecular Weight: 34140 MW
• Observed Molecular Weight: 34 kDa
• Fragment: Rabbit IgG
• Applications Notes: Western blot, 0.25-0.5 μg/ml, Human
  Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
  ELISA, 0.1-0.5 μg/ml, -