Anti-MCM2 Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-MCM2 Rabbit Monoclonal Antibody catalog # M00374-2. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

• Synonyms:

  DNA replication licensing factor MCM2;3.6.4.12; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; MCM2; BM28, CCNL1, CDCL1, KIAA0030

• Gene Name:

  DNA replication licensing factor MCM2

• UniProt:

  P49736

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human MCM2

• Clonality:

  Monoclonal

• Clone:

  Clone: 28M60

• Tissue Specificity:

  Highly expressed in substantia nigra. .

• Applications:

  WB, IHC, ICC, IF, IP, Flow Cytometry

• Field of Research:

  DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200
  IP 1:50
  FC 1:50

• Other Gene Names:

  MCM2

• Subcellular Location:

  Nucleus .

• Protein Name:

  T-cell surface glycoprotein CD4