Anti-Fibronectin Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-Fibronectin Rabbit Monoclonal Antibody catalog # M00564-3. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Fibronectin; FN; Cold-insoluble globulin; CIG; Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; FN1; FN

• Gene Name:

  Fibronectin

• UniProt:

  P02751

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Fibronectin

• Clonality:

  Monoclonal

• Clone:

  Clone: 26F78

• Tissue Specificity:

  Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine. .

• Applications:

  Flow Cytometry, IF, IHC, ICC, WB

• Field of Research:

  DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC1:50-1:200
  ICC/IF 1:50-1:200
  FC 1:50

• Other Gene Names:

  FN1

• Subcellular Location:

  Secreted, extracellular space, extracellular matrix.

• Protein Name:

  T-cell surface glycoprotein CD4