Anti-GSC Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-GSC Rabbit Monoclonal Antibody catalog # M03084-2. Tested in WB, IP applications. This antibody reacts with Human.

• Synonyms:

  TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83; TRAF4; CART1, MLN62, RNF83

• Gene Name:

  TNF receptor-associated factor 4

• UniProt:

  P56915

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human GSC

• Clonality:

  Monoclonal

• Clone:

  Clone: 22G47

• Tissue Specificity:

  Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. .

• Applications:

  WB, IP

• Field of Research:

  2339, Chromatin Modifying Enzymes, Co-Activators/Co-Repressors, Co-Factors, Epigenetics and Nuclear Signaling, Nuclear Receptors, Nuclear Signaling Pathways, Transcription

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity) . Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions. .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  IP 1:50

• Other Gene Names:

  GSC

• Subcellular Location:

  Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton .

• Protein Name:

  T-cell surface glycoprotein CD3 zeta chain