Anti-JAK1 Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-JAK1 Rabbit Monoclonal Antibody catalog # M00330-1. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Cytochrome b-245 heavy chain;1.-.-.-; CGD91-phox; Cytochrome b (558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome; CYBB; NOX2

• Gene Name:

  Cytochrome b-245 heavy chain

• UniProt:

  P23458

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human JAK1

• Clonality:

  Monoclonal

• Clone:

  Clone: 18J08

• Tissue Specificity:

  Detected in neutrophils (at protein level) . .

• Applications:

  WB

• Field of Research:

  Adaptive Immunity, Cancer, Cancer Metabolism, Immunology, Metabolism, T Cells

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H (+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000

• Other Gene Names:

  JAK1

• Subcellular Location:

  Cell membrane; Multi-pass membrane protein.

• Protein Name:

  P2X purinoceptor 1