Anti-beta Actin Mouse Monoclonal Antibody

• Description:

  Boster Bio Anti-beta Actin Mouse Monoclonal Antibody catalog # M01263-5. Tested in WB application. This antibody reacts with Human, Monkey, Mouse, Rat, Goat.

• Synonyms:

  Actin, cytoplasmic 1; Beta-actin; Actin, cytoplasmic 1, N-terminally processed; ACTB

• Gene Name:

  Actin, cytoplasmic 1

• UniProt:

  P60709

• Host:

  Mouse

• Reactivity:

  Human, Monkey, Mouse, Rat, Goat

• Immunogen:

  A synthesized peptide derived from human beta Actin

• Clonality:

  Monoclonal

• Clone:

  Clone: 17A11

• Tissue Specificity:

  Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas. Normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth.

• Applications:

  WB

• Field of Research:

  Actin, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG2b

• Applications Notes:

  WB 1:3000-1:10000

• Other Gene Names:

  ACTB

• Subcellular Location:

  Cytoplasm, cytoskeleton . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

• Protein Name:

  Glycogen synthase kinase-3 beta (gsk3b)