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Selurampanel

CAT: 0804-HY-105860-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105860-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selurampanel (BGG 492) is an orally active and competitive AMPA receptor antagonist with an IC50 of 190 nM. Selurampanel has reasonable blood-brain barrier penetration. Selurampanel can be used for epilepsy research[1][2].
CAS Number
912574-69-7
Product Name Alternative
BGG 492
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/selurampanel.html
Purity
99.41
Solubility
DMSO : 27.5 mg/mL (ultrasonic)
Smiles
CC(C1=C(C2=CC=NN2C)C=C3C(NC(N(NS(C)(=O)=O)C3=O)=O)=C1)C
Molecular Formula
C16H19N5O4S
Molecular Weight
377.42
References & Citations
[1]David Orain, et al. Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist. ChemMedChem. 2017 Feb 3;12 (3) :197-201.|[2]Edward Faught, et al. BGG492 (selurampanel), an AMPA/kainate receptor antagonist drug for epilepsy. Expert Opin Investig Drugs. 2014 Jan;23 (1) :107-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
AMPA Receptor

Alternative Products

CatalogName
T34609-01Selurampanel

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