Mouse IL-17F/Interleukin-17F ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Mouse IL-17F/Interleukin-17F ELISA Kit EZ-Set™ (DIY Antibody Pairs)

• Background: Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.
• Description: Mouse IL-17F/Interleukin-17F ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse Il17f in cell culture supernatants, serum and plasma (heparin, EDTA).
• CAS Number: 7732-18-5
• Gene Name: Il12f
• Gene ID: 257630
• UniProt: Q7TNI7
• Reactivity: Mouse
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: E.coli; Immunogen sequence: R21-A153
• Applications: ELISA
• Sample Type: cell culture supernatants, serum and plasma (heparin, EDTA)
• Detection Range: 31.2 pg/ml - 2,000 pg/ml
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Specificity: Natural and recombinant mouse Il17f