Human APLP1 PicoKine® Quick ELISA Kit

Human APLP1 PicoKine® Quick ELISA Kit

• Background: This gene encodes a member of the highly conserved amyloid precursor protein gene family. It is mapped to 19q13.12. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
• Description: Human APLP1 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human APLP1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• CAS Number: 7732-18-5
• Gene Name: APLP1
• Gene ID: 333
• UniProt: P51693
• Reactivity: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: S39-E580
• Applications: ELISA
• Detection Range: 156 pg/ml - 10,000 pg/ml
• : heparin or EDTA
• Sample Type: cell culture supernatants, serum and plasma (heparin, EDTA)
• Sensitivity: <50 pg/ml
• Storage Conditions: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)
• Reproducibility:

  Reproducibility

  To assay reproducibility, three samples with differing target protein concentrations were assayed using four different lots.

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	270	211	253	236	183	13.90	7.6%
  Sample 2	972	1440	1371	1396	1294	54.34	4.2%
  Sample 3	3395	4159	3479	3643	3669	194.45	5.3%

  *number of samples for each test n=16.
• Specificity: Natural and recombinant Human APLP1