Mouse FGF 1 Protein

CAT: 0749-PRP1152-01Size: 20 µgDry Ice: NoHazardous: No
CAT#:0749-PRP1152-01Size:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mouse FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. It is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. Intracellular Mouse FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signalin
Description
Mouse FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. It is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. Intracellular Mouse FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signalin.
Product Name Alternative
AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
Gene ID
14164
Accession Number
P61148
Tag
FGF1
Type
Cytokines and proteins
Applications
No tag
Purity
> 95 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
15.9 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized recombinant Mouse FGF1 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Protein Length
The recombinant Mouse FGF1 consists of 141 amino acids and predicts a molecular mass of 15.9 kDa.
Formulation
Lyophilized from 20 mM Tris-HCl pH 8.0, 50 mM NaCl, 0.5 mM EDTA.
Applications Notes
Mouse
Other Product Names
AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
Recommended Usage
Centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Mouse FGF1 protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E. coli
Accession Number URL
http://www.uniprot.org/uniprot/P61148
AA Sequence
Amino acid sequence derived from mouse FGF1 (Phe16-Asp155) (P61148) with an N-terminal Met was expressed.

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