Products for Research Use Only

Human CXCL1 Protein

CAT: 0749-PRP1041-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0749-PRP1041-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis
Description
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity.
Product Name Alternative
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Gene ID
2919
Accession Number
P09341
Tag
CXCL1
Type
Cytokines and proteins
Applications
No tag
Purity
> 96 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
7.9 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 1 EU per μg of the protein as determined by the LAL method
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized recombinant Human CXCL1 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles
Protein Length
The recombinant Human CXCL1 consists of 73 amino acids and predicts a molecular mass of 7.9 kDa.
Formulation
Lyophilized from sterile 20mM Tris, 50mM NaCl, pH 8.0.
Applications Notes
Human
Other Product Names
CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human CXCL1 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions
Preparation
E. coli
AA Sequence
Amino acid sequence derived from Human CXCL1 (P09341) (Ala35-Asn107) was expressed.