NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (hydrochloride)
CAT:
804-HY-148819A-04
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (hydrochloride)
- UNSPSC Description: NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) hydrochloride is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].
- Target Antigen: ADC Cytotoxin; Topoisomerase
- Type: Reference compound
- Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/nh2-bicyclo-1-1-1-pentane-7-mad-mdcpt-hydrochloride.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1.[H]Cl
- Molecular Weight: 509.94
- References & Citations: [1]Andrew C. Phillips, et al. Anti-c-met antibody drug conjugates.WO2022232834.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported