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EGFRvIII Peptide TFA

CAT: 0013-GTR19035747-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19035747-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This synthetic EGFRvIII peptide, representing the tumor-specific EGFRvIII fusion junction, is presented by HLA-A*0201 and induces CD8+ T cell activation and IFN-γ production. In vivo, it enhances antitumor immunity in glioblastoma models when combined with flagellin B, increasing CD8+ T cells, reducing Tregs and tumor burden, and improving survival.
Field of Research
Immunology & Inflammation
Molecular Weight
1079.20
Storage Conditions
-20°C
Notes
For research use only.

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