Products for Research Use Only

Recombinant Human Osteoprotegerin

CAT: 0013-GTR19034002-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19034002-01Size:10 µg
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Description
Recombinant Human Osteoprotegerin
Product Name Alternative
TNFRSF11B, Osteoclastogenesis Inhibitory Factor, Tumor Necrosis Factor Receptor Superfamily Member 11B
UniProt
O00300
Source
Escherichia coli
Endotoxin
Less than 1 EU/ug of rHuOPG as determined by LAL method.
Purity
> 95 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 �� 105 IU/mg in the presence of 10 ng/mL soluble rHuRANKL (sRANKL) .
Form
Lyophilized from a 0.2 um filtered concentrated solution in PBS.
Molecular Weight
Approximately 19.7 kDa, a single non-glycosylated polypeptide chain containing 173 amino acids.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes
For research use only.
AA Sequence
ETFPPKYLHY DEETSHQLLC DKCPPGTYLK QHCTAKWKTV CAPCPDHYYT DSWHTSDECL YCSPVCKELQ YVKQECNRTH NRVCECKEGR YLEIEFCLKH RSCPPGFGVV QAGTPERNTV CKRCPDGFFS NETSSKAPCR KHTNCSVFGL LLTQKGNATH DNICSGNSES TQK

UniProtKB · O00300

Tumor necrosis factor receptor superfamily member 11B

TR11B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00300
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFRSF11B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R9A8, O60236, Q53FX6, Q9UHP4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Apoptosis

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Molecular function

Receptor

Domain

RepeatSignal

Cellular component

Secreted