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Recombinant Murine Interleukin-6

CAT: 0013-GTR19033713-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19033713-01Size:10 µg
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Description
Recombinant Murine Interleukin-6
Product Name Alternative
B-cell hybridoma growth factor, Interleukin HP-1.
UniProt
P08505
Source
Escherichia coli
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1 EU/ug of rMuIL-6 as determined by LAL method.
Purity
> 97 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is less than 0.02 ng/ml, corresponding to a specific activity of > 5 x107 IU/mg.
Form
Lyophilized from a 0.2 μm filtered solution in 30 mM Acetic Acid, pH 3.0, 150 mM NaCl, 5 % Trehalose, 0.02 % Tween-20.
Molecular Weight
Approximately 21.7 kDa, a single non-glycosylated polypeptide chain containing 188 amino acids.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes
For research use only.
AA Sequence
MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT

UniProtKB · P08505

Interleukin-6

IL6_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P08505
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Il6
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
IL-6
EC number
—
Processing
Precursor
Secondary accessions
Q3UCQ0, Q8BN26
Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

Biological process

Acute phase

Molecular function

CytokineGrowth factor

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal

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