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OGG1

CAT: 0013-GTR19030866Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19030866Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OGG1 is a DNA glycosylase enzyme which takes part in base excision repair. OGG1 protein is the main enzyme accountable for the excision of 7, 8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which arises as a result of exposure to reactive oxygen species (ROS) . OGG1 shows beta lyase activity that nicks DNA 3'' to the lesion.
Product Name Alternative
HMMH, HOGG1, MUTM, OGH1
Conjugation
Unconjugated
Tag
Histidine
Source
Human
Origin
Recombinant protein expressed as His tage protein in E.coli
Field of Research
Epigenetics & Chromatin
Concentration
1mg/mL
Dilution
NA
Endotoxin
Not tested
Purity
≥95%
Form
Lyophilized
Solubility
Soluble in PBS at 25°C
Molecular Weight
~40 kDa
Storage Conditions
After reconstitution, store at -20°C; Avoid repeated freeze thaw
Notes
For research use only.
Applications Notes
For research use only
Tested Applications
SDS-PAGE
Host or Source
E. coli
Preservative
No preservative
AA Sequence
SSGLVPRGSHTGSMPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQCRHAQEPPAKRRKGSKGPEG

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