Recombinant Mouse M-CSF protein (His Tag)

• Background:

  Macrophage colony-stimulating factor 1 (M-csf) is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

• Abbreviation:

  M-CSF

• Synonyms:

  Ath; Ath-; Ath-1; Ath1; CD134; CD134L; OX-40L; OX4; TNFSF4; TXGP1; Tnlg2b; Txgp; Txgp1l; gp3; gp34

• UniProt:

  P07141

• Accession Number:

  P07141

• Expression System:

  E.coli

• Tag:

  C-His

• Sequence:

  Lys32-Pro187

• Applications:

  Cell culture

• Endotoxin:

  < 0.1 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 98 % as determined by reducing SDS-PAGE.

• Bioactivity:

  505 x 105 IU/mg.5

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  19.0 kDa

• Observed Molecular Weight:

  17-25 kDa

• Species:

  Mouse