Recombinant Mouse TNF Receptor II/TNF RII/TNFRSF1B/CD120b (C-Fc)

Recombinant Mouse TNF Receptor II/TNF RII/TNFRSF1B/CD120b (C-Fc)

• Background: Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF-α and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-α. TNFRSF1B mediates most of the metabolic effects of TNF-α. TNF-α-induced apoptosis suggests that it regulates TNF-α function by antagonizing its biological activity.
• Abbreviation: TNFRSF1B;CD120b
• Synonyms: TNF RII, TNF-RII, TNFRII, Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1b
• CAS Number: 9000-83-3
• UniProt: Q545P4
• Accession Number: Q545P4
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-Fc
• Sequence: Val23-Gly258
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 60-85 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.