Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)

Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)

• Background: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.
• Abbreviation: Interleukin-11;IL-11
• Synonyms: Interleukin, IL-11, Interleukin-11, Zcyto1, Zcyto10, Il11, AGIF, interleukin 11
• CAS Number: 9000-83-3
• UniProt: P47873
• Accession Number: P47873
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-Fc
• Sequence: Pro22-Leu199
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 50-60 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.