Recombinant Mouse Trefoil Factor 1/TFF1 Protein (His Tag)

Recombinant Mouse Trefoil Factor 1/TFF1 Protein (His Tag)

• Background: Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing.It originates from musculus and highly expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and form non-covalent complexes with the mucin MUC5AC. TFF1 is down-regulated during the progression from gastritis to gastric dysplasia to gastric cancer, although it is up-regulated in breast and prostate cancers. TFF1 inhibits the formation of calcium oxalate crystals, and its excretion in the urine is reduced in patients with kidney stones.
• Abbreviation: Trefoil Factor 1;TFF1
• Synonyms: Bcei, Protein pS2, Ps2, Tff1, Trefoil factor 1
• CAS Number: 9000-83-3
• UniProt: Q08423
• Accession Number: Q08423
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-His
• Sequence: Gln22-Phe87
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 15 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.