Recombinant Mouse Semaphorin-4C/SEMA4C Protein (Fc Tag)

Recombinant Mouse Semaphorin-4C/SEMA4C Protein (Fc Tag)

• Background: Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
• Abbreviation: Semaphorin-4C;SEMA4C
• Synonyms: M-Sema F, S4c, Sema I, Sema4c, Semacl1, Semai, Semaphorin I, Semaphorin-4C, Semaphorin-C-like 1
• CAS Number: 9000-83-3
• UniProt: Q64151
• Accession Number: Q64151
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-Fc
• Sequence: Ala21-Gly664
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 115-125 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.