Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

• Background: HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
• Synonyms: AI503787, HAVcr-1, Hepatitis A virus cellular receptor 1 homolog, KIM-1, Kidney injury molecule 1, T cell membrane protein 1, TIM-1, Timd1
• CAS Number: 9000-83-3
• UniProt: Q5QNS5
• Accession Number: NP_001160104.1
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-His-Fc
• Sequence: Tyr 22-Thr 212
• Purity: > 97 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 80-85 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.