Recombinant Mouse LAMP2/CD107b Protein (His Tag)

Recombinant Mouse LAMP2/CD107b Protein (His Tag)

• Background: LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.
• Synonyms: CD107b, LGP-B, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, LampII, Mac3
• CAS Number: 9000-83-3
• UniProt: P17047
• Accession Number: P17047-1
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-His
• Sequence: Leu 26-Asn 379
• Purity: > 97 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 70-80 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.