Recombinant Mouse EphA3 Protein (Fc Tag)

Recombinant Mouse EphA3 Protein (Fc Tag)

• Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
• Synonyms: AW492086, Cek4, ETK1, End3, Hek, Hek4, Mek4, Tyro4
• CAS Number: 9000-83-3
• UniProt: Q8BRB1
• Accession Number: NP_034270.1
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-hFc
• Sequence: Met1-His541
• Applications: ELISA
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: Immobilized mouse EFNA5-His at 10 μg/ml (100 μl/well) can bind mouse EPHA3-Fc, The EC50 of rat mouse EPHA3-Fc is 12.3-28.9 ng/ml.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 96 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.