Recombinant Human CD7/Leu-9 (C-6His-Avi) Biotinylated

• Background:

  T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes, NK-cells, pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions, T-cell/B-cell interaction during early lymphoid development, T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However, the function of the CD7 protein in the immune system is still largely unknown.

• Abbreviation:

  CD7; Leu-9

• Synonyms:

  CD7; GP40; T-Cell Antigen CD7; T-Cell Leukemia Antigen; T-Cell Surface Antigen Leu-9; TP41

• UniProt:

  P09564

• Accession Number:

  P09564

• Expression System:

  HEK293 Cells

• Conjugation:

  Biotinylated

• Tag:

  C-His-Avi

• Sequence:

  Ala26--Pro180

• Field of Research:

  Immunology

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  19.3 kDa

• Observed Molecular Weight:

  30-35 kDa

• Species:

  Human