Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-Fc)

• Background:

  Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

• Abbreviation:

  BTN1A1

• Synonyms:

  BT; BTN; BTN1A1; Butyrophilin Subfamily 1 Member A1

• UniProt:

  Q13410

• Accession Number:

  Q13410

• Expression System:

  HEK293 Cells

• Tag:

  C-Fc

• Sequence:

  Ala27-Arg242

• Field of Research:

  Cardiovascular

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  50.8 kDa

• Observed Molecular Weight:

  60-80 kDa

• Species:

  Human