Recombinant Human Stanniocalcin 1/STC-1 (C-6His)

Recombinant Human Stanniocalcin 1/STC-1 (C-6His)

• Background: Stanniocalcin 1 (STC-1) is a homodimeric glycoprotein hormone that is involved in calcium and phosphate homeostasis. It was originally identified in bony fishes, where elevation of calcium in serum causes the release of STC from the endocrine glands called the corpuscles of Stannius. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. It is also a biomarker of brain and lung cancer progression. STC1 signals through inhibitory G-protein modulates CGRP receptor spatial localization during osteoblastogenesis and may function as a regulatory factor interacting with calcitonin peptide members during bone formation.
• Abbreviation: Stanniocalcin 1;STC-1
• Synonyms: STC-1, STC1, STCSTC-1, Stanniocalcin 1, stanniocalcin-1
• CAS Number: 9000-83-3
• UniProt: P52823
• Accession Number: P52823
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-His
• Sequence: Thr18-Ala247
• Field of Research: Signal Transduction;Cell biology;Cancer;metabolism;
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 28-36 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.