Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-mFc)
CAT:
763-PKSH033858-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-mFc)
- Background: CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
- Abbreviation: TNFSF7;CD70
- Synonyms: CD27 ligand, CD27L, CD27LG, CD70, CD70 antigen, TNFSF7, Tumor necrosis factor ligand superfamily member 7
- CAS Number: 9000-83-3
- UniProt: P32970
- Accession Number: P32970
- Host: HEK293 Cells
- Origin Species: Human
- Tag: C-mFc
- Sequence: Gln45-Pro193
- Field of Research: Cancer;immunology;Stem cells
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 50-60 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.