Recombinant Human CCL1/I-309 Protein

Recombinant Human CCL1/I-309 Protein

• Background: Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
• Abbreviation: CCL1;I-309
• Synonyms: CCL1, C-C Motif Chemokine 1, SCYA1, Small-Inducible Cytokine A1, T Lymphocyte-Secreted Protein I-309
• CAS Number: 9000-83-3
• UniProt: P22362
• Accession Number: P22362
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Lys24-Lys96
• Field of Research: immunology
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 10 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.