Recombinant Human CRADD/RAIDD Protein
CAT:
763-PKSH033738-02
Size:
10 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human CRADD/RAIDD Protein
- Background: Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues; with particularly high expression in the adult heart; testis; liver; skeletal muscle; fetal liver; and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2; and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
- Abbreviation: CRADD;RAIDD
- Synonyms: CRADD, Caspase and RIP Adapter with Death Domain, Death Domain-Containing Protein CRADD, RAIDD, RIP-Associated Protein with A Death Domain
- CAS Number: 9000-83-3
- UniProt: P78560
- Accession Number: P78560
- Host: E. coli
- Origin Species: Human
- Tag: None
- Sequence: Met1-Glu199
- Field of Research: Cell biology;Cancer
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 21 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.