Recombinant Human EGF Protein

CAT: 0763-PKSH033687-01Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0763-PKSH033687-01Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Epidermal growth factor (EGF) is a small 53 amino acid residue long protein that contains three disulfide bridges. It is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. This protein shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites.

Abbreviation

EGF

Synonyms

EGF; Epidermal Growth Factor; Pro-Epidermal Growth Factor; Urogastrone

UniProt

P01133

Accession Number

P01133

Expression System

E.coli

Tag

C-His

Sequence

Asn971-Arg1023

Applications

Cell culture

Field of Research

Signal Transduction; Cell biology; Cancer

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

506

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

7.2 kDa

Observed Molecular Weight

9-11 kDa

Species

Human

UniProtKB · P01133

Pro-epidermal growth factor

EGF_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P01133
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EGF
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: EGF
EC number: —
Processing: Precursor
Secondary accessions: B4DRK7, E7EVD2, E9PBF0, Q52LZ6

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Disease variantPrimary hypomagnesemia

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Growth factor

Cellular component

Membrane

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PDER100034-01	Recombinant Rat Epidermal Growth Factor/EGF protein (His tag)
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E-KAB-0023	Human EGF Antibody Pair Set
AN300375L-01	Recombinant Phospho-EGF Receptor (Tyr845) Monoclonal Antibody

Alternative Products

Catalog	Name
ARP4541-01	Recombinant Human Protein
TP727636	Human Recombinant Protein