Recombinant Human TrkB/NTRK2 Protein (His Tag)
CAT:
763-PKSH033579-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human TrkB/NTRK2 Protein (His Tag)
- Background: The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.
- Abbreviation: TrkB;NTRK2
- Synonyms: BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, NTRK2, Neurotrophic Tyrosine Kinase Receptor Type 2, TRKB, Trk-B, TrkB Tyrosine Kinase, Tropomyosin-Related Kinase B
- CAS Number: 9000-83-3
- UniProt: Q16620
- Accession Number: Q16620
- Host: HEK293 Cells
- Origin Species: Human
- Tag: C-His
- Sequence: Cys32-His430
- Field of Research: Neuroscience;Cancer;metabolism
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 60-105 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.