Recombinant Human SIRPB1/CD172b Protein (His Tag)

Recombinant Human SIRPB1/CD172b Protein (His Tag)

• Background: Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK.
• Abbreviation: SIRPB1;CD172b
• Synonyms: CD172 antigen-like family member B, CD172b, SIRP-beta-1, SIRPB1, Signal-regulatory protein beta-1
• CAS Number: 9000-83-3
• UniProt: O00241
• Accession Number: O00241
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-His
• Sequence: Glu30-Glu362
• Field of Research: Signal Transduction;
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 45-55 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.