Recombinant Human RBP4 Protein

• Background:

  Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue; and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma; the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.

• Abbreviation:

  RBP4

• Synonyms:

  PRBP; Plasma Retinol-Binding Protein; RBP; RBP4; RDCCAS; Retinol-Binding Protein 4

• Accession Number:

  P02753

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Glu19-Leu201

• Field of Research:

  Signal Transduction; Cardiovascular; Cancer; epigenetics and nuclear signal; metabolism

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 90 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  21.2 kDa

• Observed Molecular Weight:

  20 kDa

• Formulation:

  2

• Species:

  Human