Recombinant Human TGFB2 Protein
CAT:
763-PKSH033139-02
Size:
10 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human TGFB2 Protein
- Background: Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
- Abbreviation: TGFB2
- Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Polyergin, TGF-beta-2, TGFB2, Transforming growth factor beta-2
- CAS Number: 9000-83-3
- UniProt: P61812
- Accession Number: P61812
- Host: HEK293 Cells
- Origin Species: Human
- Tag: None
- Sequence: Ala303-Ser414
- Applications: Cell culture
- Field of Research: Signal Transduction;Cell biology;Cancer;metabolism;Stem cells
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 30-180pg/ml.
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 12 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.