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Recombinant Human NFYA Protein

CAT: 0763-PKSH032824-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0763-PKSH032824-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor ; which is composed of three components; NF-YA; NF-YB and NF-YC; binds to CCAAT motifs in the promoter regions in a variety of genes. NFYA forms a highly conserved transcription factor which stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters; for example in type 1 collagen; albumin and beta-actin genes.
Abbreviation
NFYA
Synonyms
CAAT Box DNA-Binding Protein Subunit A; NF-YA; NFYA; Nuclear Transcription Factor Y Subunit A; Nuclear Transcription Factor Y Subunit Alpha
UniProt
P23511
Accession Number
P23511-2
Expression System
E.coli
Tag
None
Sequence
Met 1-Ser318
Field of Research
Epigenetics and Nuclear Signaling
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
33.9 kDa
Observed Molecular Weight
40&60&70 kDa
Species
Human

UniProtKB · P23511

Nuclear transcription factor Y subunit alpha

NFYA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23511
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NFYA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8IXU0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsTranscriptionTranscription regulation

Cellular component

Nucleus

PTM

Phosphoprotein
Product Datasheet
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