Recombinant Human IL18RAP/IL1R7 Protein (His Tag)

• Background:

  IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

• Abbreviation:

  IL18RAP; IL1R7

• Synonyms:

  IL1R; ACPL; CD218b; CDw218b; IL-18RAcP; IL18RB; IL-18Rbeta; IL-18R-beta; IL-1R7; IL-1R-7; IL-1RAcPL; IL1R7; IL18RAP; IL-1RcPL; CDw218b; IL18Rβ Accessory protein like; Accessory protein-like; CD218 antigen-like family member B; I18RA; IL 18RAcP; IL 1R accessory protein like; IL 1R7; IL 1RAcPL; IL-18 receptor accessory protein; IL18Rbeta; IL-1R accessory protein-like; Interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; Interleukin-18 receptor beta chain

• UniProt:

  O95256

• Accession Number:

  O95256

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Sequence:

  Phe20-Arg356

• Field of Research:

  Cancer; immunology

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

• Storage Conditions:

  Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

• Calculated Molecular Weight:

  39.4 kDa

• Observed Molecular Weight:

  56 kDa

• Formulation:

  Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

• Species:

  Human