Recombinant Human CLIC1 Protein (His Tag)

Recombinant Human CLIC1 Protein (His Tag)

• Background: Chloride Intracellular Channel Protein 1 (CLIC1) belongs to the Chloride Channel CLIC family and contains one GST C-terminal domain. CLIC1 can be expressed in various cell types, but it is especially prominent in the heart, placenta, liver, kidney, and pancreas. CLIC1 can insert into membranes and form chloride ion channels. The channel activity depends on the pH. CLIC1 membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. CLIC1 is also involved in the regulation of the cell cycle.
• Abbreviation: CLIC1
• Synonyms: CLIC1, Chloride Channel ABP, Chloride Intracellular Channel Protein 1, G6, NCC27, Nuclear Chloride Ion Channel 27, Regulatory Nuclear Chloride Ion Channel Protein, hRNCC
• CAS Number: 9000-83-3
• UniProt: O00299
• Accession Number: O00299
• Host: E. coli
• Origin Species: Human
• Tag: N-His
• Sequence: Met 1-Lys241
• Field of Research: Signal Transduction;Cancer;metabolism;
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 30-35 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.